Advanced Topics in Gender-affirming Hormone Therapy: Challenges and Complications
Saturday, May 17, 2025
8:00 AM – 9:00 AM
CE: 1.00 AAPA Category 1 CME
PAs provide gender-affirming hormone therapy in primary care and specialty care settings. This interactive, case-based session will focus on navigating advanced prescribing challenges and complications faced by PAs when providing masculinizing and feminizing gender-affirming care to adult transgender and gender non-binary patients. After a brief review of the foundations of gender-affirming care, this session will delve into the following: pros and cons regarding hormone formulation, managing medication side effects, contraception considerations, adjunctive therapies, peri- and post-operative management, significant laboratory abnormalities, and management and care for non-binary patients. PAs will leave this session prepared to manage complications and challenges in providing masculinizing and feminizing hormone therapy to adult transgender and gender non-binary patients.
Learning Objectives:
At the conclusion of this session, participants should be able to:
Describe foundations of pharmacologic management for masculinizing and feminizing gender-affirming hormone therapy
Explain side effects, common symptoms, and abnormal laboratory findings encountered in gender-affirming hormone therapy
Select hormone formulations, adjunct therapies, and contraception options based on patient characteristics and goals
Discuss risks and complications of adjunct pharmacologic gender-affirming treatments
Manage peri- and post-operative gender-affirming care